22x12.5 is an awfully wide wheel. It will depend on your offset and the actual tire specs. Most people seem to be running 9 or 10" wide wheels with aftermarket offsets of -12 to 0 and up to 34.5" tall tires without issue.
I don't believe the 12.5 will work on anything more than the 17" rim without cutting. You could get away with a 10"...which will get you 11.5....I think.
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